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Full-Time
On-Site

Principal Research Associate, Protein Design

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Description

Moderna is seeking a highly motivated Principal Research Associate to join their team and support early research and development in next-generation biologics. This role involves applying innovative, high-throughput screening technologies within functional genomics and cell engineering to identify and validate lead therapeutic candidates across various disease areas. The successful candidate will develop, optimize, and deploy advanced lentiviral-based screening platforms and collaborate with scientists and cross-functional teams to translate screening insights into therapeutic programs.

What We're Looking For

Design, execute, and analyze experiments independently, with guidance from Scientists as needed.,Critically evaluate data, document observations, troubleshoot experiments, and maintain thorough records in an electronic lab notebook.,Communicate experimental results, insights, and challenges effectively during team meetings and cross-functional discussions.,Maintain and expand primary human cell cultures and cancer cell lines.,Generate engineered cell lines through transient transfection, stable transduction, selection, and validation.,Perform core cell and molecular biology techniques, including PCR, molecular cloning, flow cytometry, and Western blotting.,Produce and titer lentiviral vectors to support screening workflows.,Optimize and execute pooled lentiviral screening workflows to enable massively parallel screening of diverse biologics.

Ideal Candidate

Bachelor's degree with 5+ years of experience or Master's degree with 2+ years of experience in Biology, Biochemical Engineering, Biotechnology, or a related field.

Minimum Education

Bachelor's Degree or Master's Degree

Hard Skills

mRNA
Cell Culture
Lentiviral
PCR
Flow Cytometry
Molecular cloning
Western blotting
Lentiviral-based screening
Biotechnology experience
Biochemical engineering
Data analysis
Experimental design

Soft Skills

Highly motivated
Talented
Collaborative
Critical evaluation
Effective communication
Teamwork
Problem-solving

Benefits

Health insurance
Paid time off
Adoption assistance

Special Commitments

Must be willing to work on-site, full-time presence at a Moderna location required; not eligible for remote work.

About the Company

M

Moderna, Inc.

Moderna is a biotechnology company pioneering a new class of medicines made of messenger RNA (mRNA). The company's platform builds on continuous advances in basic and applied mRNA science, delivery technology and manufacturing, and has allowed the development of therapeutics and vaccines for infectious diseases, immuno-oncology, rare diseases, cardiovascular diseases and autoimmune diseases.

Innovative
Science-driven
Collaborative
Fast-paced
Mission-oriented
View all jobs at Moderna, Inc.

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